REVIEW ON NOVEL AND RECENT CHANGE IN FLUROQUINOLONES

The oldest Fluoroquinolones derivatives i.e. ciprofloxacine , oflaxacin causes various side effects and also produce cross resistance to other derivative of fluoroquinolenes,they produce some resistance of bacterial infection. Now a days this problems are very critical; the need of novel potent antimicrobial agents for this effect or problems overcome. The need for novel potent antimicrobial agents is seen worldwide. The WHO release priority list detailing the discovery and development of novel antibiotics WHO priority list, ESKAPE pathogens are listed amongs “ Critical” and “high” priority groups. So development of antibiotics is urgently needed against this pathogens. • To study and investigate the effect, used and action of recent Fluoroquinolones. • Delafloxacin, Finafloxacin and Zibofloxacin to compare these agents with each other and contrast them with ciprofloxacin, an older Fluoroquinolones.