DETERMINATION OF OXYGEN TENSION IN PERIPHERAL NEUROPATHY AND DIABETES USING NIRS METHOD

According to WHO, India had 69.2 million people living with diabetes in 2015 and is expected to rise by more than a 5th from 406 million in 2018 to 511 million in 2030. Diabetes currently affects over 425 million people worldwide. Peripheral neuropathy is a severe nerve damage caused by chronic blood sugar and diabetes. Foot ulcer is a wound that occurs approximately 15 percent of patients with diabetes and is commonly located on the bottom of the foot. Various studies have indicated that peripheral vascular disease is related to tissue hypoxia and clinical device monitors uses pulse oximetry principle to measure changes of light absorption in oxygenated and deoxygenated blood. In this project we intend to develop a portable device to assess oxygen tension near foot ulcerate area using NIRS (Near infrared spectroscopy) method in diabetic subjects. The results can be visualized in the LCD and Visual display. The main purpose of oxygen tension estimation is to have a better understanding in wound healing potential, assessment of success in revascularization, and predictability of amputation level and the study the need of hyperbaric oxygen in therapy.