PREPARATION OF SECONDARY ALCOHOLS FROM 1-N-BENZYL 9,10- DIHYDROLYSERGOL |
Author(s): |
Mehak Rohilla |
Keywords: |
9,10- Dihydrolysergal, TFAA, DMSO, TEA, Grignard reagent, ergoline. |
Abstract |
The Swern oxidation of 1-N-benzyl 9,10- dihydrolysergol using TFAA, DMSO, and TEA afforded 1-N-benzyl- 9,10- dihyrolysergal. The aldehyde moiety so produced was used for introduction of various substituents by employing Grignard reaction to yield new ergoline derivatives. |
Other Details |
Paper ID: IJSARTV Published in: Volume : 4, Issue : 1 Publication Date: 1/1/2018 |
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