SELF EMULSIFYING DRUG DELIVERY SYSTEM |
Author(s): |
S. Gokulakannan |
Keywords: |
oral bioavailability, GIT ,oil-in- water emulsion, dissolution rate, SEDDS. |
Abstract |
Self emulsifying drug delivery system are isotropic mixtures of oils, surfactants and co- solvents that spontaneous form oil-in-water emulsion upon mild agitation in GIT.These system have been developed to improve the oral bioavailability of drug . SEDDS are administered orally in soft or hard gelatin capsules.once they reach the stomach , they are dispersed by the churing of the stomach content and form stable emulsion.This emulsification process can improve the dissolution rate and absorption of the drug , leading to enhance bioavailability. |
Other Details |
Paper ID: IJSARTV Published in: Volume : 9, Issue : 12 Publication Date: 12/1/2023 |
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